Physics Department, Ludwig Maximilians University Amalienstr. 54, D-80799 München, Germany ++49 (0)89 2180 2317 (Fax -2050) mail@dieterb.de dieter.braun@lmu.de => University Homepage (information below is out of date) |
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Stefan Duhr (Nanotemper) |
Franz Weinert | Philipp
Baaske (Nanotemper) |
Christoph
Wienken (Nanotemper) |
Philipp Reineck | Mario Herzog | Christof Mast | Ingmar Schön
(now: ETH) |
In the past, we studied for the
first
time thermophoresis of DNA, i.e. fast movement of
DNA from hot to cold in a
temperature
gradient. It can be used to accumulate DNA
million-fold by thermal
convection.
A similar convection flow was later used to
implement a fast and small DNA
replicating
PCR
reaction.
Both experiments are the
foundation
for new biotechnological approaches to diagnostics.
At the same time they show new
ways
for hypothesis on the origin of life in pores of
vulcanic rock at the ocean
seafloor.
We will continue to explore new
basic
effects of microscopic temperature fields. For
example we want to use a
sinusoidal
temperature
oscillation to yield a lock-in based
frequency space approach for
kinetic
measurements inside cells.
Stefan Duhr and Philipp
Baaske have founded the startup company NanoTemper Technologies
for thermophoretic and optical
melting curve analytics.
What follows is a list of publications and a list of talks:
Publications | |
Observation of
Slip Flow in Thermophoresis Franz M. Weinert and Dieter Braun, Physical Review Letters 101, 168301 (2008) |
|
Microscale
Fluid
Flow
Induced by Thermoviscous Expansion Along a Traveling Wave Franz M. Weinert, Jonas A. Kraus, Thomas Franosch and Dieter Braun, Physical Review Letters 100, 164501 (2008) |
|
|
Melting curve analysis in a snapshot Philipp Baaske, Stefan Duhr and Dieter Braun, Applied Physics Letters 91, 133901 (2007) |
From the cover: Extreme Accumulation of Nucleotides in Simulated Hydrothermal Pore Systems Philipp Baaske, Franz M. Weinert, Stefan Duhr, Kono H. Lemke, Michael J. Russell, Dieter Braun, PNAS 104, 9346–9351 (2007) Commentary by Eugene V. Koonin PNAS 104, 9105-9106 (2007) |
|
Size
Determination
of
(Bio)conjugated Water-Soluble Colloidal Nanoparticles:
A Comparison of Different Techniques R. A. Sperling, T. Liedl, S. Duhr, S. Kudera, M. Zanella, C.-A. J. Lin, W. H. Chang, D. Braun, and W. J. Parak, J. Phys. Chem. C 111, 11552-11559 (2007) |
|
Thermodiffusion of Charged Colloids:
Single-Particle Diffusion Jan K. G. Dhont, Simone Wiegand, Stefan Duhr and Dieter Braun, Langmuir 23, 1674-1683 (2007) |
|
From the cover: Why molecules move along a temperature gradient Stefan Duhr and Dieter Braun, PNAS 103, 19678–19682 (2006) Commentary by Dean Astumian, PNAS 104, 3-4 (2007) |
|
Optothermal
Molecule
Trapping
by Opposing Fluid Flow with Thermophoretic Drift Stefan Duhr and Dieter Braun, Physical Review Letters 97, 038103 (2006) (Movie: DNA Accumulation) |
|
Thermophoretic
Depletion
Follows
Boltzmann Distribution Stefan Duhr and Dieter Braun, Physical Review Letters 96, 168301 (2006) |
|
Nonequilibrium Thermodynamics of Wealth Condensation Dieter Braun, Physica A, 369, 714-722 (2006) (more on dedicated pages) |
|
Convective
polymerase
chain
reaction around micro immersion heater Martin Hennig and Dieter Braun, Applied Physics Letters 87, 183901 (2005) Discussed in Nature Methods 3, 8-9 (2006) |
|
The Role of Metal
Nanoparticles in Remote Release of Encapsulated Materials A.G. Skirtach, C. Déjugna, D. Braun, A.S. Susha, A.L. Rogach, W.J. Parak, H. Möhwald, G.B. Sukhorukov, Nano Letters 7:1371-1377 (2005) |
|
|
Two-dimensional
colloidal
crystals
formed by thermophoresis and convection Stefan Duhr and Dieter Braun, Applied Physics Letters 86:131921 (2005) |
Thermophoresis of DNA determined by microfluidic fluorescence Stefan Duhr, Silvia Arduini and Dieter Braun, European Physical Journal E 15:277-286 (2004) (Movie: DNA, Beads) |
|
PCR by Thermal Convection Dieter Braun, Modern Physics Letters B, 18:775-784 (2004) |
|
Imaging Neuronal Seal Resistance on Silicon
Chip using Fluorescent Voltage-Sensitive Dye Dieter Braun and Peter Fromherz, Biophysical Journal 87:1351-1359 (2004) (Movie of Membrane Voltage over Time) |
|
|
Thermal
force approach to molecular evolution Dieter Braun and Albert Libchaber, Physical Biology 1:P1-P8 (2004) |
|
Lock-In
by molecular multiplication Dieter Braun and Albert Libchaber, Applied Physics Letters 83:5554-5556 (2003) |
|
Exponential
DNA
Replication
by Laminar Convection Dieter Braun, Noel L. Goddard and Albert Libchaber, Physical Review Letters 91:158103 (2003) (Article by Physical Review Focus) (Nature News Article) (Movie: DNA Replication, Beads showing convection flow) |
|
Multiplexed
DNA Quantification by Spectroscopic Shift of Two Microsphere Cavities Frank Vollmer, Stephen Arnold, Dieter Braun, Iwao Teraoka and Albert Libchaber, Biophysical Journal 85:1974–1979 (2003) (Article by Biophotonics International) |
|
Trapping
of DNA by Thermophoretic Depletion and Convection
Dieter Braun and Albert Libchaber, Physical Review Letters 89:188103 (2002) (Article in Physics Today Feb03, page2) (Article in Biophotonics International) (Article in New Scientist 2Nov02) (Movie: Trapping of Plasmid DNA, Trapping of 200nm Beads) |
Computer-based
Photon Counting Lock-In for Phase Detection at the Shot Noise Limit Dieter Braun and Albert Libchaber, Optics Letters 27:1418-1420 (2002) Download LabView Source Code |
|
|
Protein
detection by optical shift of a resonant microcavity
F. Vollmer, D. Braun, A. Libchaber, M. Khoshsima, I. Teraok and S. Arnold, Applied Physics Letters 80:4057-4059 (2002) |
|
Nontrivial
Bookkeeping:
a
mechanical Perspective Robert Fischer and Dieter Braun, Physica A 324:266-271 (2003) (more on dedicated pages) |
|
Transfer
Potentials
shape
and equilibrate Monetary Systems Robert Fischer and Dieter Braun, Physica A 321:605-618 (2003) (more on dedicated pages) |
|
No
correlation of focal contacts and close adhesion by
comparing GFP-vinculin and fluorescence interference of DiI Yoriko Iwanaga, Dieter Braun and Peter Fromherz, European Biophysical Journal 30:17-26 (2001) |
|
Fast
Voltage Transients in Capacitive Silicon-to-Cell Stimulation
observed with a Luminescent Molecular Electronic Probe Dieter Braun and Peter Fromherz, Physical Review Letters 86:2905-2908 (2001) (Movie of Membrane Voltage over Time) |
|
Assets
and liabilities are the momentum of particles and antiparticles displayed in Feynman-graphs Dieter Braun, Physica A 290:491-500 (2001) (more on dedicated pages) |
|
Adhesion
Proteins for a Tight Neuron-Electrode Contact Helga Sorribas, Dieter Braun, Lukas Leder, Peter Sonderegger, Louis Tiefenauer, Journal of Neuroscience Methods 104:133-141 (2001). |
|
Capacitive
Stimulation
of
Mammalian Cells on Silicon Chips imaged at Optical Resolution with Voltage-Sensitive Dyes PhD thesis at the Technische Universität München (2000) |
|
Fluorescence
Interferometry of Neuronal Cell Adhesion on Microstructured Silicon. Dieter Braun and Peter Fromherz, Physical Review Letters 81:5241-5244 (1998) (FLIC pages) |
|
Fluorescence
Interference-Contrast Microscopy of Cell Adhesion on Oxidized Silicon. D. Braun, P. Fromherz, Applied Physics A 65:341-348 (1997) (FLIC pages) |
|
Untersuchung der
Struktur der
Silizium-Neuron-Kopplung durch Fluoreszenzfarbstoffe Dieter Braun. Diplomarbeit at the Technische Universität München (1996) |
.... list not updated recently
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Physik Modern, University
Munich (2004)
American
Biophysics Conference,
Baltimore (2004)
Rowland
Institute, Boston (2003)
Japanese
Biophysical Meeting,
Nagaoka (2003)
American
Biophysics Conference, San Antonio (2003)
Center
for Studies in Physics and
Biology, Rockefeller University, New York (2003)
Chemical
Physics Seminar University of
Pittsburgh (2003)
TRILab-Talk
Rockefeller University, New
York (2003)
Mainstreaming
Microfluidics Meeting,
Boston (2003)
Gordon
Conference on Electrical Processes in Polymers (2002)
Biophysics
Seminar Ludwig-Maximillians University Munich (2002)
International
Meeting on Thermal Diffusion IMT5, Kopenhagen (2002)
Seminar
of Courant Institute , New York University, New York (2001)
Modern
Methods in Biology,
Schlössmann-Seminar (2001)